Abstract
lukF-PV was present in 36% of skin and soft tissue infection (SSTI)-derived methicillin-susceptible Staphylococcus aureus (MSSA) strains and comprised six distinct clones, which contained fewer enterotoxin genes than strains without lukF-PV. Clinical presentations and outcomes of lukF-PV(+) methicillin-resistant S. aureus (MRSA) and MSSA SSTIs were comparable. In multivariable analysis, the presence of lukF-PV remained a significant predictor for incision and drainage among MSSA strains.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / pharmacology*
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Bacterial Toxins / genetics*
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Child
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Child, Preschool
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Exotoxins / genetics*
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Female
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Humans
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Infant
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Leukocidins / genetics*
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Male
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Methicillin / pharmacology*
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Middle Aged
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Molecular Typing
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New York / epidemiology
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Prevalence
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Skin Diseases, Bacterial / epidemiology*
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Skin Diseases, Bacterial / microbiology
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Skin Diseases, Bacterial / pathology
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Soft Tissue Infections / epidemiology*
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Soft Tissue Infections / microbiology
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Soft Tissue Infections / pathology
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Staphylococcal Infections / epidemiology*
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Staphylococcal Infections / microbiology
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Staphylococcal Infections / pathology
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Staphylococcus aureus / classification
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Staphylococcus aureus / genetics
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Staphylococcus aureus / isolation & purification*
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Treatment Outcome
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Young Adult
Substances
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Anti-Bacterial Agents
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Bacterial Toxins
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Exotoxins
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Leukocidins
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Panton-Valentine leukocidin
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Methicillin