Osteopoikilosis: a major diagnostic problem solved by bone scintigraphy

Rev Esp Med Nucl Imagen Mol. 2012 Mar-Apr;31(2):93-6. doi: 10.1016/j.remn.2011.04.010. Epub 2011 Jun 11.


Osteopoikilosis (OPK) is a rare disease with an unknown etiology. Although a benign condition, it may lead to diagnostic problems when the patient undergoes diagnostic imaging of the skeletal system due to various reasons like malignancy. Herein, we report 2 cases with OPK causing difficulties in the final diagnosis of the cases which was resolved with the contribution of bone scintigraphy and clinical follow-up.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Aged
  • Back Pain / diagnostic imaging
  • Back Pain / etiology
  • Bone Neoplasms / diagnosis
  • Carpal Bones / diagnostic imaging
  • Diagnosis, Differential
  • Femur / diagnostic imaging
  • Humans
  • Multimodal Imaging*
  • Osteopoikilosis / complications
  • Osteopoikilosis / diagnostic imaging*
  • Pelvic Bones / diagnostic imaging
  • Positron-Emission Tomography*
  • Stomach Ulcer / complications
  • Stomach Ulcer / surgery
  • Tomography, X-Ray Computed*
  • Whole Body Imaging*