Fibrosarcoma of the head and neck

Laryngoscope. 1990 Aug;100(8):799-802. doi: 10.1288/00005537-199008000-00001.


A review of 118 archival cases originally diagnosed as fibrosarcoma of the head and neck is presented. Sites of involvement were the sinonasal region, upper aerodigestive tract, skin, and soft tissues. Review of the pathologic specimens applying strict histopathologic criteria including immunohistochemical techniques reclassified many of the tumors as malignant fibrous histiocytoma, monophasic synovial sarcoma-like neoplasm, or dermatofibrosarcoma protuberans. Improved clinical outcome correlated significantly with lesser tumor size, lower histologic grade, and negative surgical margins. Location in the skin or soft tissue tended to convey improved survival, although not to a level of statistical significance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Fibrosarcoma* / epidemiology
  • Fibrosarcoma* / pathology
  • Head and Neck Neoplasms* / epidemiology
  • Head and Neck Neoplasms* / pathology
  • Histiocytoma, Benign Fibrous / epidemiology
  • Histiocytoma, Benign Fibrous / pathology
  • Humans
  • Life Tables
  • Male
  • Prognosis
  • Survival Analysis
  • Texas / epidemiology