Risk factors of stroke-associated pneumonia in Chinese patients

Neurol Res. 2011 Jun;33(5):508-13. doi: 10.1179/016164111X13007856084205.

Abstract

Objective: To explore the risk factors for stroke-associated pneumonia (SAP).

Methods: A retrospective research study was carried out to investigate the clinical data of 1435 patients admitted to the neurological intensive care unit at our university hospital between 1 January 2000 and 31 December 2009.

Results: A multi-factorial analysis produced the following results: (1) SAP is 1.113 times more likely to occur for each 1-year increase in age; (2) diabetic patients are 1.612 times more likely to develop SAP than non-diabetic patients; (3) the incidence of SAP decreases by a factor of 0.890 with a one-point increase in the Glasgow coma scale score; (4) nasal feeding patients are 4.981 times more likely to develop SAP than non-nasal feeding patients; (5) patients who use H₂-receptor blocking agents are 2.837 times more likely to develop SAP than those who do not; (6) patients who preventively use antibiotics are 2.675 times more likely to develop SAP than those who do not; (7) patients whose hospitalization periods are >20 days are 0.500 times more likely to develop SAP than those who do not; (8) patients who suffer from tracheal intubation are 2.980 times more likely to develop SAP than those who do not; and (9) patients who suffer from tracheal incision are 2.190 times more likely to develop SAP than those who do not.

Conclusions: SAP was more closely related with diabetes, age, consciousness, days of hospitalization, tracheal intubation, tracheal incision, nasal feeding treatment, and the application of H₂-receptor blocking agents and antimicrobials.

MeSH terms

  • Acute Disease
  • Age Distribution
  • Aged
  • Asian People
  • China / epidemiology
  • Cross Infection / complications
  • Cross Infection / drug therapy
  • Cross Infection / ethnology*
  • Female
  • Humans
  • Intensive Care Units
  • Male
  • Middle Aged
  • Pneumonia, Bacterial / complications
  • Pneumonia, Bacterial / drug therapy
  • Pneumonia, Bacterial / ethnology*
  • Retrospective Studies
  • Risk Factors
  • Stroke / complications
  • Stroke / ethnology*