Prenatal Diagnosis of Congenital Cytomegalovirus Infection: Two Decades Later

Am J Obstet Gynecol. 1990 Aug;163(2):447-50. doi: 10.1016/0002-9378(90)91173-a.


Cytomegalovirus is the most common cause of congenital infection in the United States, yet there has been little progress in the prenatal diagnosis of this intrauterine infection. We present evidence that viral culture of amniotic fluid may be a useful adjunct procedure, when performed as part of the antenatal evaluation of suspected fetal cytomegalovirus infection.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amniocentesis
  • Amniotic Fluid / microbiology*
  • Cytomegalovirus / isolation & purification*
  • Cytomegalovirus Infections / congenital*
  • Cytomegalovirus Infections / diagnosis
  • Female
  • Fetal Diseases / diagnosis*
  • Humans
  • Infant, Newborn
  • Pregnancy
  • Prenatal Diagnosis*
  • Ultrasonography