Abstract
Herein we report the synthesis of water-soluble polyglycerol-dendronized perylenediimides with a single reactive group that undergoes high-yielding click reactions. Single-molecule studies and target-specific biolabeling are reported, including the highly specific labeling of proteins on the surface of living bacterial and mammalian cells.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Bacterial Proteins / metabolism
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Click Chemistry*
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Dendrimers / chemical synthesis
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Dendrimers / chemistry*
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Dendrimers / metabolism
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Escherichia coli / cytology
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Fluorescent Dyes / chemical synthesis
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Fluorescent Dyes / chemistry*
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Fluorescent Dyes / metabolism
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Glycerol / chemistry
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HeLa Cells
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Humans
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Imides / chemistry*
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Molecular Imaging
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Perylene / analogs & derivatives*
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Perylene / chemistry
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Polymers / chemistry
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Solubility
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Staining and Labeling
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Substrate Specificity
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Water / chemistry*
Substances
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Bacterial Proteins
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Dendrimers
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Fluorescent Dyes
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Imides
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Polymers
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perylenediimide
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Water
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polyglycerol
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Perylene
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Glycerol