Presynaptic mechanism for long-term potentiation in the hippocampus

J M Bekkers; C F Stevens

doi:10.1038/346724a0

Presynaptic mechanism for long-term potentiation in the hippocampus

Nature. 1990 Aug 23;346(6286):724-9. doi: 10.1038/346724a0.

Authors

J M Bekkers¹, C F Stevens

Affiliation

¹ Salk Institute, Howard Hughes Medical Institute, La Jolla, California 92037.

PMID: 2167454
DOI: 10.1038/346724a0

Abstract

Experiments analysing the statistical properties of synaptic transmission, before and after the induction of long-term potentiation (LTP), suggest that expression of LTP largely arises in a presynaptic mechanism--an increased probability of transmitter release.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Animals
Cells, Cultured
Evoked Potentials
Hippocampus / physiology*
In Vitro Techniques
Kinetics
Neurons / physiology
Rats
Synapses / physiology*
Synaptic Transmission*