Objective: To report a case of hiccups secondary to intrathecal (IT) morphine infusion.
Methods: Case report and discussion.
Results: The hiccups in our patient resolved on substitution of IT morphine infusion with hydromorphone.
Discussion: We report a case of a 44-year-old man who developed persistent hiccups with IT morphine infusion pump therapy. The hiccups persisted despite various nonpharmacological and pharmacological measures. The untoward symptom resolved after substitution of IT hydromorphone for IT morphine.