Calcinosis cutis: part II. Treatment options

J Am Acad Dermatol. 2011 Jul;65(1):15-22; quiz 23-4. doi: 10.1016/j.jaad.2010.08.039.

Abstract

Because calcinosis cutis is a rare syndrome, there is a notable lack of controlled clinical trials on its treatment. The efficacy of calcinosis treatment has only been reported in single cases or small case series. No treatment has been generally accepted as standard therapy, although various treatments have been reported to be beneficial, including warfarin, bisphosphonates, minocycline, ceftriaxone, diltiazem, aluminium hydroxide, probenecid, intralesional corticosteroids, intravenous immunoglobulin, curettage, surgical excision, carbon dioxide laser, and extracorporeal shock wave lithotripsy.

Publication types

  • Review

MeSH terms

  • Biopsy, Needle
  • Calcinosis / diagnosis
  • Calcinosis / drug therapy*
  • Calcinosis / surgery*
  • Ceftriaxone / therapeutic use
  • Combined Modality Therapy
  • Drug Therapy, Combination
  • Education, Medical, Continuing
  • Evidence-Based Medicine
  • Female
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Immunohistochemistry
  • Laser Therapy / methods
  • Lasers, Gas / therapeutic use
  • Male
  • Minocycline / therapeutic use
  • Prognosis
  • Recurrence
  • Risk Assessment
  • Severity of Illness Index
  • Skin Diseases / diagnosis
  • Skin Diseases / drug therapy*
  • Skin Diseases / surgery*
  • Treatment Outcome
  • Warfarin / therapeutic use

Substances

  • Immunoglobulins, Intravenous
  • Warfarin
  • Ceftriaxone
  • Minocycline