Cognitive and neurodevelopmental effects of antiepileptic drugs

Epilepsy Behav. 2011 Sep;22(1):9-16. doi: 10.1016/j.yebeh.2011.04.009. Epub 2011 Jun 17.


This article primarily represents the contributions of two young investigators to the understanding of the neuropsychological consequences of epilepsy and its treatment. The authors have reviewed two key areas of importance: the complex relationship between cognitive dysfunction and epilepsy and the risks of cognitive dysfunction in children as a consequence of in utero exposure to antiepileptic drug treatment. The work of two young investigators is presented and future research needs are outlined.

Publication types

  • Review

MeSH terms

  • Anticonvulsants / adverse effects*
  • Brain / drug effects
  • Brain / embryology
  • Brain / growth & development*
  • Cognition Disorders / complications
  • Cognition Disorders / etiology*
  • Epilepsy / complications
  • Epilepsy / drug therapy*
  • Female
  • Fetal Development / drug effects
  • Humans
  • Neuropharmacology / methods
  • Neuropharmacology / trends
  • Pregnancy
  • Prenatal Exposure Delayed Effects*


  • Anticonvulsants