Genome of Multidrug-Resistant Uropathogenic Escherichia Coli Strain NA114 From India

J Bacteriol. 2011 Aug;193(16):4272-3. doi: 10.1128/JB.05413-11. Epub 2011 Jun 17.

Abstract

Uropathogenic Escherichia coli (UPEC) causes serious infections in people at risk and has a significant environmental prevalence due to contamination by human and animal excreta. In developing countries, UPEC assumes importance in certain dwellings because of poor community/personal hygiene and exposure to contaminated water or soil. We report the complete genome sequence of E. coli strain NA114 from India, a UPEC strain with a multidrug resistance phenotype and the capacity to produce extended-spectrum beta-lactamase. The genome sequence and comparative genomics emanating from it will be significant in under-standing the genetic makeup of diverse UPEC strains and in boosting the development of new diagnostics/vaccines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Drug Resistance, Multiple, Bacterial*
  • Genome, Bacterial*
  • Humans
  • India / epidemiology
  • Molecular Sequence Data
  • Urinary Tract Infections / epidemiology
  • Urinary Tract Infections / microbiology*
  • Uropathogenic Escherichia coli / genetics*

Substances

  • Anti-Bacterial Agents

Associated data

  • GENBANK/CP002797