Oxaliplatin-induced coronary artery spasm: first report of an important side-effect

BMJ Case Rep. 2009:2009:bcr06.2008.0334. doi: 10.1136/bcr.06.2008.0334. Epub 2009 Feb 26.


A 67-year-old woman with metastatic colorectal cancer was given her first oxaliplatin infusion as part of the XELOX protocol. She developed chest pain with ECG changes leading subsequently to a diagnosis of coronary artery spasm. To our knowledge, this is the first report of oxaliplatin-induced coronary artery spasm.