This paper presents a case of ocular involvement during acute renal failure caused by hantavirus. A 34-year-old man suffered from sudden visual loss during acute onset fever with nausea and renal failure. The ophthalmologic examination showed myopia in both eyes and no signs of infection but virological studies revealed an infection with hantavirus. During treatment of the renal failure the myopia improved spontaneously. Transient myopia is a typical ocular involvement during infections with hantavirus which leads to renal failure.