Errors in the administration of intravenous medications in hospital and the role of correct procedures and nurse experience
- PMID: 21690248
- PMCID: PMC3228265
- DOI: 10.1136/bmjqs-2011-000089
Errors in the administration of intravenous medications in hospital and the role of correct procedures and nurse experience
Abstract
Background: Intravenous medication administrations have a high incidence of error but there is limited evidence of associated factors or error severity.
Objective: To measure the frequency, type and severity of intravenous administration errors in hospitals and the associations between errors, procedural failures and nurse experience.
Methods: Prospective observational study of 107 nurses preparing and administering 568 intravenous medications on six wards across two teaching hospitals. Procedural failures (eg, checking patient identification) and clinical intravenous errors (eg, wrong intravenous administration rate) were identified and categorised by severity.
Results: Of 568 intravenous administrations, 69.7% (n = 396; 95% CI 65.9 to 73.5) had at least one clinical error and 25.5% (95% CI 21.2 to 29.8) of these were serious. Four error types (wrong intravenous rate, mixture, volume, and drug incompatibility) accounted for 91.7% of errors. Wrong rate was the most frequent and accounted for 95 of 101 serious errors. Error rates and severity decreased with clinical experience. Each year of experience, up to 6 years, reduced the risk of error by 10.9% and serious error by 18.5%. Administration by bolus was associated with a 312% increased risk of error. Patient identification was only checked in 47.9% of administrations but was associated with a 56% reduction in intravenous error risk.
Conclusions: Intravenous administrations have a higher risk and severity of error than other medication administrations. A significant proportion of errors suggest skill and knowledge deficiencies, with errors and severity reducing as clinical experience increases. A proportion of errors are also associated with routine violations which are likely to be learnt workplace behaviours. Both areas suggest specific targets for intervention.
Conflict of interest statement
Figures
Similar articles
-
Association of interruptions with an increased risk and severity of medication administration errors.Arch Intern Med. 2010 Apr 26;170(8):683-90. doi: 10.1001/archinternmed.2010.65. Arch Intern Med. 2010. PMID: 20421552
-
Changes in medication administration error rates associated with the introduction of electronic medication systems in hospitals: a multisite controlled before and after study.BMJ Health Care Inform. 2020 Aug;27(3):e100170. doi: 10.1136/bmjhci-2020-100170. BMJ Health Care Inform. 2020. PMID: 32796084 Free PMC article.
-
Errors in preparation and administration of intravenous medications in the intensive care unit of a teaching hospital: an observational study.Aust Crit Care. 2008 May;21(2):110-6. doi: 10.1016/j.aucc.2007.10.004. Epub 2008 Apr 2. Aust Crit Care. 2008. PMID: 18387813
-
Systematic evidence review of rates and burden of harm of intravenous admixture drug preparation errors in healthcare settings.BMJ Open. 2017 Dec 28;7(12):e015912. doi: 10.1136/bmjopen-2017-015912. BMJ Open. 2017. PMID: 29288174 Free PMC article. Review.
-
An overview of intravenous-related medication administration errors as reported to MEDMARX, a national medication error-reporting program.J Infus Nurs. 2006 Jan-Feb;29(1):20-7. doi: 10.1097/00129804-200601000-00005. J Infus Nurs. 2006. PMID: 16428997 Review.
Cited by
-
From Pregnancy Pains to Paralysis: An Erroneous Intrathecal Digoxin Administration Case Report and Review of Medical Errors.Cureus. 2024 Jul 17;16(7):e64764. doi: 10.7759/cureus.64764. eCollection 2024 Jul. Cureus. 2024. PMID: 39156299 Free PMC article.
-
Frontline nursing staff's perceptions of intravenous medication administration: the first step toward safer infusion processes-a qualitative study.BMJ Open Qual. 2024 Jun 27;13(2):e002809. doi: 10.1136/bmjoq-2024-002809. BMJ Open Qual. 2024. PMID: 38942437 Free PMC article.
-
Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors.Drug Des Devel Ther. 2024 Mar 22;18:899-908. doi: 10.2147/DDDT.S444581. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 38533429 Free PMC article.
-
Risk Factors Associated with Medication Administration Errors in Children: A Prospective Direct Observational Study of Paediatric Inpatients.Drug Saf. 2024 Jun;47(6):545-556. doi: 10.1007/s40264-024-01408-6. Epub 2024 Mar 5. Drug Saf. 2024. PMID: 38443625 Free PMC article.
-
Evaluating deviations and considerations in daily practice when double-checking high-risk medication administration: A qualitative study using the FRAM.Heliyon. 2024 Feb 1;10(4):e25637. doi: 10.1016/j.heliyon.2024.e25637. eCollection 2024 Feb 29. Heliyon. 2024. PMID: 38380025 Free PMC article.
References
-
- National Patient Safety Agency Safety in doses: improving the use of medicine in the NHS. London: National Patient Safety Agency, 2009
-
- Phillips J, Beam S, Brinker A. Retrospective analysis of mortalities associated with medication errors. Am J Health Syst Pharm 2001;58:1835–41 - PubMed
-
- Westbrook JI, Woods A, Rob MI, et al. Association of interruptions with increased risk and severity of medication administration errors. Arch Intern Med 2010;170:683–90 - PubMed
-
- Barker KN, Flynn EA, Pepper GA, et al. Medication errors observed in 36 healthcare facilities. Arch Intern Med 2002;162:1897–903 - PubMed
-
- Colen HB, Neef C, Schuring RW. Identification and verification of critical performance dimensions: phase I of the systematic process redesign of drug distribution. Pharm World Sci 2003;25:118–25 - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical