Secondary Sjögren's syndrome and disease activity of rheumatoid arthritis

Rev Assoc Med Bras (1992). 2011 May-Jun;57(3):319-22. doi: 10.1590/s0104-42302011000300015.


Objective: To study the relationship of the presence of secondary SS with disease activity, duration in RA.

Methods: Eighty two patients with RA were submitted to Schirmer test, minor salivary gland biopsy, questionnaire on sicca symptoms, DAS-28 4v determination.

Results: In this population, 20 (24.3%) patients fulfilled the American-European classification criteria for secondary SS. No relation could be found between the presence of secondary SS and disease activity (p = 0.31) and RA duration (p = 0.95).

Conclusion: Appearance of Secondary SS in RA patients is independent of RA duration or activity.

MeSH terms

  • Arthritis, Rheumatoid / complications*
  • Dry Eye Syndromes / diagnosis
  • Dry Eye Syndromes / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Sjogren's Syndrome / diagnosis
  • Sjogren's Syndrome / drug therapy
  • Sjogren's Syndrome / etiology*
  • Xerostomia / diagnosis
  • Xerostomia / etiology