Abstract
An efficient formal synthesis of SCH 351448 was accomplished through the tandem cross-metathesis (CM)/oxa-Michael, the 1,4-syn aldol, the tandem oxidation/oxa-Michael, and the Suzuki coupling reaction.
© 2011 American Chemical Society
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Aldehydes / chemistry*
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Lactones / chemical synthesis*
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Lactones / chemistry
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Molecular Structure
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Oxidation-Reduction
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Stereoisomerism
Substances
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Aldehydes
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Lactones
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SCH 351448