[Diazepam (Relanium)--current views on its action with special reference to developmental age]

Wiad Lek. 1990 Apr 15;43(8):336-42.
[Article in Polish]

Abstract

In a survey of the pertinent literature the pharmacological and toxicodynamic, effects, metabolism and mechanism of action of diazepam in experimental animals and humans are discussed. Particular attention is paid to the effects of diazepam given during the developmental age on the development and function of the central nervous system in mammals.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Animals
  • Anxiety / drug therapy*
  • Anxiety / metabolism
  • Brain / drug effects*
  • Brain / metabolism
  • Diazepam / pharmacokinetics
  • Diazepam / pharmacology
  • Diazepam / therapeutic use*
  • Female
  • Fetus / drug effects*
  • Fetus / metabolism
  • Humans
  • Infant, Newborn / metabolism*
  • Maternal-Fetal Exchange / drug effects
  • Maternal-Fetal Exchange / physiology
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Pregnancy Complications / metabolism
  • Rats
  • Receptors, GABA-A / drug effects*
  • Receptors, GABA-A / metabolism

Substances

  • Receptors, GABA-A
  • Diazepam