Effect of mycoprotein on blood lipids

Am J Clin Nutr. 1990 Oct;52(4):646-50. doi: 10.1093/ajcn/52.4.646.


This metabolic study was designed to investigate the effects of mycoprotein on blood lipids. Mycoprotein is a food produced by continuous fermentation of Fusarium graminearum (Schwabe) on a carbohydrate substrate. Two groups of subjects with slightly raised cholesterol concentrations took part in the 3-wk study. The experimental group was fed mycoprotein in place of meat and the control diet contained meat. There was no change in plasma cholesterol in the control group but there was a 13% reduction in the mycoprotein group. Low-density lipoprotein (LDL) increased in the control group by 12% and decreased by 9% in the mycoprotein group. High-density lipoprotein (HDL) decreased by 11% in the control group but increased by 12% in the mycoprotein group. In each case the group ANOVA differences between variables were statistically significant. It is clear from these results that lipid variables are advantageously altered by mycoprotein consumption.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Apolipoprotein A-I
  • Apolipoproteins A / blood
  • Apolipoproteins B / blood
  • Cholesterol / blood
  • Diet
  • Dietary Fiber / administration & dosage
  • Fatty Acids, Unsaturated / administration & dosage
  • Female
  • Food, Formulated*
  • Humans
  • Lipids / blood*
  • Lipoproteins, HDL / blood
  • Lipoproteins, LDL / blood
  • Male
  • Meat
  • Middle Aged


  • Apolipoprotein A-I
  • Apolipoproteins A
  • Apolipoproteins B
  • Dietary Fiber
  • Fatty Acids, Unsaturated
  • Lipids
  • Lipoproteins, HDL
  • Lipoproteins, LDL
  • Cholesterol