Surgical treatment of achalasia: transabdominal versus transthoracic cardiomyotomy

Ann Thorac Cardiovasc Surg. 2011;17(3):254-9. doi: 10.5761/atcs.oa.09.01506.

Abstract

Background: Achalasia is a primary esophageal motor disorder involving the body of the esophagus and lower esophageal sphincter. The mechanism is destruction of the myenteric plexus after a viral infection. Multiple methods of treatment with variable results induced in achalasia.

Materials and methods: We analyzed 70 patients with achalasia that underwent surgical treatment with transabdominal or transthoracic cardiomyotomy from 1982 to 2008 in Mashhad (Ghaem and Omid) hospital and at least 2 years follow up for evaluated result of surgery.

Results: The mean age was 39.2 ± 9.42 years and the M/F = 0.89. The most common symptom was dysphagia (100%). The interval between beginnings of symptoms to a definitive diagnosis was 10.6 ± 8.3 month. The ratio between the two techniques was 35/35 = 1. In 67.1% of patients, a previous history of pneumatic dilation was reported. Long-term good results after surgery were seen in 77.2% of patients. Recurrence after surgical treatment was seen in 22.8%. A comparison of the two techniques (with or without antireflux surgery), showed a greater failure rate in transabdominal cardiomyotomy without the antireflux protocol (8/15 = 40%), but by the chi- square test, the difference was not statistically significant (P = 0.107). The most common complication after surgery was esophageal leakage (2.85%), and mortality was zero. In recurrence, most patients underwent pneumatic dilation (9/16 = 56.2%), and if surgery was needed, all patients underwent a transthoracic approach with antireflux treatment.

Conclusion: Based on the good, long-term results with the surgical treatment of achalasia, surgery is recommended in most patients. A transthoracic or transabdominal approach had good, long-term results, but a transthoracic approach had better results and usually did not need antireflux surgery.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdomen / surgery*
  • Adolescent
  • Adult
  • Cardia / surgery*
  • Chi-Square Distribution
  • Deglutition Disorders / etiology
  • Digestive System Surgical Procedures* / adverse effects
  • Esophageal Achalasia / complications
  • Esophageal Achalasia / diagnostic imaging
  • Esophageal Achalasia / surgery*
  • Female
  • Humans
  • Iran
  • Male
  • Middle Aged
  • Radiography
  • Recurrence
  • Risk Assessment
  • Risk Factors
  • Thoracotomy* / adverse effects
  • Time Factors
  • Treatment Outcome
  • Young Adult