"Going KiNativ": probing the Native Kinome

Chem Biol. 2011 Jun 24;18(6):683-4. doi: 10.1016/j.chembiol.2011.06.001.


In this issue, Patricelli et al. (2011) describe an in situ chemoproteomics approach (KiNativ™) for profiling the kinome and kinome response to specific kinase inhibitors that enables characterization of inhibitor interactions with endogenously expressed kinases in native conditions.

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