Special article: Future directions in malignant hyperthermia research and patient care

Anesth Analg. 2011 Nov;113(5):1108-19. doi: 10.1213/ANE.0b013e318222af2e. Epub 2011 Jun 27.


Malignant hyperthermia (MH) is a complex pharmacogenetic disorder of muscle metabolism. To more closely examine the complexities of MH and other related muscle disorders, the Malignant Hyperthermia Association of the United States (MHAUS) recently sponsored a scientific conference at which an interdisciplinary group of experts gathered to share new information and ideas. In this Special Article, we highlight key concepts and theories presented at the conference along with exciting new trends and challenges in MH research and patient care.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Calcium / physiology
  • Heat Stroke / physiopathology
  • Homeostasis / physiology
  • Humans
  • Malignant Hyperthermia / diagnosis
  • Malignant Hyperthermia / epidemiology
  • Malignant Hyperthermia / genetics
  • Malignant Hyperthermia / physiopathology
  • Malignant Hyperthermia / therapy*
  • Muscle, Skeletal / physiopathology
  • Muscular Diseases / physiopathology
  • Patient Care
  • Patient Safety
  • Research


  • Calcium