doi: 10.4103/0974-7753.77519.
Emerging issues with the current keratin-associated protein nomenclature
Affiliations
- PMID: 21712897
- PMCID: PMC3107952
- DOI: 10.4103/0974-7753.77519
Item in Clipboard
Emerging issues with the current keratin-associated protein nomenclature
Int J Trichology.
2010 Jul.
Abstract
Keratin associated proteins (KAPs) are a class of proteins that associate with keratin intermediate filament proteins through disulphide linkages to give fibres such as hair and wool their unique properties. Up to 90 proteins from some 25 families have been identified and this does not include polymorphic variants of individual proteins within these families. The existence of this diverse group of proteins has been known for some 75 years but, despite this, there is still no universally accepted nomenclature for them. This paper sets out the case for revising the current system to deal with this nomenclature issue.
Keywords: Hair; KAP; Keratin.
Conflict of interest statement
Similar articles
-
An updated nomenclature for keratin-associated proteins (KAPs).Int J Biol Sci. 2012;8(2):258-64. doi: 10.7150/ijbs.3278. Epub 2012 Jan 12. Int J Biol Sci. 2012. PMID: 22298953 Free PMC article. Review.
-
Diversity of Trichocyte Keratins and Keratin Associated Proteins.Adv Exp Med Biol. 2018;1054:21-32. doi: 10.1007/978-981-10-8195-8_3. Adv Exp Med Biol. 2018. PMID: 29797265 Review.
-
Characterisation of low abundance wool proteins through novel differential extraction techniques.Electrophoresis. 2010 Jun;31(12):1937-46. doi: 10.1002/elps.201000053. Electrophoresis. 2010. PMID: 20564690
-
Ovine keratome: identification, localisation and genomic organisation of keratin and keratin-associated proteins.Anim Genet. 2018 Oct;49(5):361-370. doi: 10.1111/age.12694. Epub 2018 Jul 30. Anim Genet. 2018. PMID: 30062723
-
Expression and purification of high sulfur and high glycine-tyrosine keratin-associated proteins (KAPs) for biochemical and biophysical characterization.Protein Expr Purif. 2018 Jun;146:34-44. doi: 10.1016/j.pep.2017.12.006. Epub 2018 Jan 31. Protein Expr Purif. 2018. PMID: 29391282
Cited by
-
Variation in the caprine keratin-associated protein 15-1 (KAP15-1) gene affects cashmere fibre diameter.Arch Anim Breed. 2019 Mar 26;62(1):125-133. doi: 10.5194/aab-62-125-2019. eCollection 2019. Arch Anim Breed. 2019. PMID: 31807622 Free PMC article.
-
Identification of the key proteins associated with different hair types in sheep and goats.Front Genet. 2022 Sep 23;13:993192. doi: 10.3389/fgene.2022.993192. eCollection 2022. Front Genet. 2022. PMID: 36212123 Free PMC article.
-
Paleoproteomics.Chem Rev. 2022 Aug 24;122(16):13401-13446. doi: 10.1021/acs.chemrev.1c00703. Epub 2022 Jul 15. Chem Rev. 2022. PMID: 35839101 Free PMC article. Review.
-
Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine.Genes (Basel). 2019 Oct 26;10(11):848. doi: 10.3390/genes10110848. Genes (Basel). 2019. PMID: 31717789 Free PMC article.
-
A primer for ZooMS applications in archaeology.Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2109323119. doi: 10.1073/pnas.2109323119. Epub 2022 May 10. Proc Natl Acad Sci U S A. 2022. PMID: 35537051 Free PMC article. Review.
References
-
- Marshall RC, Orwin DF, Gillespie JM. Structure and biochemistry of mammalian hard keratin. Electron Microsc Rev. 1991;4:47–83. - PubMed
-
- Parry DA, Steinert PM. Intermediate Filament Structure. New York: Springer-Verlag; 1995. Intermediate filament associated proteins; pp. 123–44.
-
- Powell BC, Rogers GE. Differentiation in hard keratin tissues: Hair and related structures. In: Leigh F, Watt RF, Lane B, editors. Keratinocyte Handbook. Cambridge: Cambridge University Press; 1994. pp. 401–36.
-
- Goddard DR, Michaelis L. Derivatives of keratin. J Biol Chem. 1934;112:361–71.
-
- Stein WH, Moore S. Chromatography of amino acids on starch columns. Separation of phenylalanine, leucine, isoleucine, methionine, tyrosine, and valine. J Biol Chem. 1948;176:337–65. - PubMed
