Isolation and characterization of phytoconstituents from Chlorophytum borivilianum

Pharmacognosy Res. 2010 Nov;2(6):343-9. doi: 10.4103/0974-8490.75452.


Background: The present communication deals with the identification and characterization of bioactive principles from the roots of Chlorophytum borivilianum.

Method: Methanolic extract and its fractions were used to isolate different phytoconstituents. The structures of isolated compounds were characterized and elucidated with chemical and spectroscopic techniques such as Infra Red, Nuclear Mass Resonace and Mass spectroscopy experiments. Fatty acids were characterized by GC-MS analysis.

Result: Three Fatty acids were isolated and confirmed. One sterol stigmasterol was isolated. One new saponin named as Chlorophytoside-I (3β, 5α, 22R, 25R)-26-(β-D-glucopyranosyloxy)-22-hydroxy-furostan-12-one-3 yl O-β-D-galactopyranosyl (1-4) glucopyranoside was isolated.

Conclusion: The roots of Chlorophytum borivilianum contain three important fatty acids, common sterol stigmasterol and one furostanol saponins.

Keywords: Chlorophytoside-I; Chlorophytum borivilianum; fatty acids; stigmasterol.