Phytochemical investigation and hair growth studies on the rhizomes of Nardostachys jatamansi DC

Pharmacogn Mag. 2011 Apr;7(26):146-50. doi: 10.4103/0973-1296.80674.


Nardostachys jatamansi DC rhizomes were subjected to extraction, fractionation, and isolation of terpenoid compounds. Three terpenoid compounds were isolated which are nardal, jatamansic acid, and nardin. These compounds were identified based on physical and spectral data (UV, IR,(1)H and(13)C NMR, 2D NMR, Mass) and comparison with authentic compounds. The crude extract, fractions, and two of the isolated compounds were tested for their hair growth activity. The hair growth studies showed good activities for the extract, fraction, and the isolated compounds.

Keywords: Hair growth; Nardostachys jatamansi; jatamansic acid; nardin; rhizomes.