Adoptive cell therapy for patients with melanoma

J Cancer. 2011;2:360-2. doi: 10.7150/jca.2.360. Epub 2011 Jun 15.


Adoptive cell therapy can be an effective treatment for some patients with advanced cancer. This report summarizes clinical trial results from the Surgery Branch, NCI, investigating tumor infiltrating lymphocytes (TIL) and gene engineered peripheral blood T cells for the therapy of patients with melanoma and other solid tumors.

Keywords: NY-ESO-1; TIL; interleukin-2; lymphodepletion; melanoma.