Quality of life in HIV/AIDS

Indian J Sex Transm Dis AIDS. 2010 Jul;31(2):75-80. doi: 10.4103/0253-7184.74971.


Given the longevity achievable with current prophylactic and therapeutic strategies for persons with HIV infection, quality of life (QOL) has emerged as a significant medical outcome measure, and its enhancement has an important goal. This review highlights the relevance and complexity of physical, psychological, and social factors as determinants of health-related quality of life in HIV-infected persons. Existing data suggest that physical manifestations, antiretroviral therapy, psychological well-being, social support systems, coping strategies, spiritual well-being, and psychiatric comorbidities are important predictors of QOL in this population. Consequently, the impact of HIV infection on the dimensions of QOL, including physical and emotional well-being, social support systems, and life roles, has emerged as a key issue for persons infected with HIV.

Keywords: AIDS; HIV; antiretroviral therapy; anxiety; coping; depression; psychosocial; quality of life; social support.