Malignant fibrous histiocytoma developing in bone 44 years after shrapnel trauma

Cancer. 1990 Nov 15;66(10):2229-32. doi: 10.1002/1097-0142(19901115)66:10<2229::aid-cncr2820661032>;2-x.


Tumors induced by foreign bodies are uncommon in humans, but they are a relatively common occurrence in some experimental animals. The development of sarcoma in association with metallic foreign bodies has rarely been reported. The development of a malignant fibrous histiocytoma in a 65-year-old man 44 years after shrapnel fragments lodged in his left arm is described. The literature regarding metallic foreign body-induced cancer in humans is reviewed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / etiology*
  • Foreign Bodies / complications*
  • Foreign Bodies / diagnostic imaging
  • Histiocytoma, Benign Fibrous / diagnostic imaging
  • Histiocytoma, Benign Fibrous / etiology*
  • Humans
  • Humerus / injuries*
  • Male
  • Radiography
  • Time Factors