PET in vasculitis

Ann N Y Acad Sci. 2011 Jun;1228:64-70. doi: 10.1111/j.1749-6632.2011.06021.x.

Abstract

[(18) F]Fluorodeoxyglucose positron emission tomography (FDG PET) can be used to visualize large-vessel inflammation in giant-cell arteritis, Takayasu arteritis, and other types of aortitis. In patients with symptoms compatible with polymyalgia rheumatica, findings of increased FDG-uptake in the shoulders, hips, as well as the spinous processes of the cervical and lumbar spine, may suggest this diagnosis. In patients with giant-cell arteritis, there is increased metabolic activity within the aortic wall on FDG PET scintigraphy, indicating inflammation of the aorta, which may be a predictor of a higher potential for aortic dilatation.

Publication types

  • Review

MeSH terms

  • Fluorodeoxyglucose F18
  • Giant Cell Arteritis / diagnosis
  • Giant Cell Arteritis / pathology
  • Humans
  • Positron-Emission Tomography / methods*
  • Takayasu Arteritis / diagnosis
  • Takayasu Arteritis / pathology
  • Vasculitis / diagnosis*
  • Vasculitis / pathology

Substances

  • Fluorodeoxyglucose F18