Accuracy and clinical utility of a portable coagulometer in an emergency setting

J Med Assoc Thai. 2011 Feb;94 Suppl 1:S89-93.

Abstract

Background: There are limited data concerning accuracy of portable coagulometer in emergency setting.

Objective: To evaluate the accuracy of the CoaguChek XS international normalized ratio (INR) monitor compared to the standard laboratory method in emergency department.

Material and method: Emergency room patients who required coagulation test were recruited. Parallel INR measurements between portable coagulometer and standard laboratory were performed.

Results: Fifty-five patients with a mean age of 59.1 +/- 15.7 years (20-87) were included. Men constituted 56.4%. Indications for testing were as follows: acute stroke 72.7%; abnormal bleeding 7.3%; taking anticoagulant 7.3%; and others 12.7%. Mean time +/- SD used from blood drawn to INR result report was 65.02 +/- 24.5 minutes for standard laboratory and 1 minute for portable coagulometer. Mean difference of INR result from portable coagulometer and standard laboratory was 0.02 +/- 0.13 and an excellence correlation between INR (r = 0.969) was demonstrated. There was no significant difference between the INR value from the two methods (p = 0.34).

Conclusion: The use of portable coagulometer (CoaguChek XS) in emergency setting was accurate and required less time. Acute ischemic stroke patients are likely to benefit from a timely clinical decision making for thrombolysis medication.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Coagulation Disorders / diagnosis*
  • Clinical Laboratory Techniques*
  • Emergency Service, Hospital
  • Female
  • Hospitals, Teaching
  • Humans
  • International Normalized Ratio / instrumentation*
  • International Normalized Ratio / standards*
  • Male
  • Middle Aged
  • Point-of-Care Systems / standards*
  • Predictive Value of Tests
  • Reproducibility of Results