Bilateral bone-marrow examinations in small-cell anaplastic carcinoma of the lung

Acta Pathol Microbiol Scand A. 1979 Jan;87(1):59-62. doi: 10.1111/j.1699-0463.1979.tb00024.x.


Bilateral bone-marrow examinations from the posterior iliac crests were routinely performed as a pretreatment staging procedure in 89 consecutive patients with small-cell anaplastic carcinoma of the lung. Bone-marrow involvement was found in 20 patients (22.5%), in 9 (10.1%) only on one side, and in 11 (12.4%) on both sides. Aspiration was found to be significantly superior to biopsy, being positive in 25 examinations as compared with 14 positive biopsies. Compared with unilateral bone-marrow examination the positive findings increased by approximately 30%. Bilateral bone-marrow examinations are recommended in patients in whom the detection of bone-marrow metastases will have therapeutic implications.

MeSH terms

  • Biopsy, Needle
  • Bone Marrow / pathology*
  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / pathology
  • Carcinoma, Small Cell / pathology*
  • Female
  • Humans
  • Ilium
  • Lung Neoplasms / pathology*
  • Male
  • Middle Aged
  • Neoplasm Metastasis