Selective laser trabeculoplasty in uncontrolled pseudoexfoliation glaucoma

Ophthalmic Surg Lasers Imaging. Sep-Oct 2011;42(5):390-3. doi: 10.3928/15428877-20110630-01. Epub 2011 Jul 7.

Abstract

Background and objective: To assess the efficacy and safety of selective laser trabeculoplasty (SLT) in uncontrolled pseudoexfoliation glaucoma (PEXG).

Patients and methods: Fifty-seven eyes (57 patients) with uncontrolled PEXG and intra-ocular pressure (IOP) greater than 23 mm Hg underwent SLT. All received ophthalmic evaluation preoperatively and at intervals postoperatively. IOP was measured at 1 hour, 1 day, 1 week, and 1, 3, 6, and 12 months postoperatively. During follow-up, patients were treated with topical anti-glaucoma medications as necessary.

Results: One year postoperatively, mean IOP in all patients decreased from 26.01 ± 2.5 to 17.8 ± 2.8 mm Hg (31.5%; P < .001). Mean medications per patient decreased from 2.8 to 2.3. Complications included conjunctival redness and infection within 1 day postoperatively in 30 eyes (67%). One hour after SLT treatment, an increase in IOP greater than 5 mm Hg was detected in two eyes (3.5%) and resolved within 24 hours with topical medication.

Conclusion: SLT is safe and effective in patients with PEXG.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Exfoliation Syndrome / physiopathology
  • Exfoliation Syndrome / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Intraocular Pressure
  • Laser Therapy*
  • Lasers, Solid-State*
  • Male
  • Middle Aged
  • Trabeculectomy / methods*