Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2011 Sep;106(6):913-22.
doi: 10.1017/S0007114511001176. Epub 2011 May 16.

Strawberry Anthocyanin and Its Association With Postprandial Inflammation and Insulin

Affiliations
Randomized Controlled Trial

Strawberry Anthocyanin and Its Association With Postprandial Inflammation and Insulin

Indika Edirisinghe et al. Br J Nutr. .

Abstract

The present study investigates the effect of strawberry antioxidants in beverage form on meal-induced postprandial inflammatory and insulin responses in human subjects. Overweight adults (n 24) consumed a high-carbohydrate, moderate-fat meal (HCFM) accompanied by either a strawberry or a placebo beverage in a cross-over design. Postprandial changes in plasma anthocyanins, their metabolites, insulin, glucose and inflammatory markers were assessed for 6 h. The postprandial concentrations of pelargonidin sulfate and pelargonidin-3-O-glucoside were significantly increased when the strawberry beverage was consumed concurrently with the HCFM compared with the placebo beverage (P < 0·001). The strawberry beverage significantly attenuated the postprandial inflammatory response as measured by high-sensitivity C-reactive protein and IL-6 (P < 0·05) induced by the HCFM. It was also associated with a reduction in postprandial insulin response (P < 0·05). Collectively, these data provide evidence for favourable effects of strawberry antioxidants on postprandial inflammation and insulin sensitivity.

Similar articles

See all similar articles

Cited by 44 articles

See all "Cited by" articles

Publication types

MeSH terms

LinkOut - more resources

Feedback