The antifungal antibiotic sinefungin as a very active inhibitor of methyltransferases and of the transformation of chick embryo fibroblasts by Rous sarcoma virus

Biochem Biophys Res Commun. 1978 Nov 14;85(1):371-6. doi: 10.1016/s0006-291x(78)80052-7.
No abstract available

MeSH terms

  • Adenosine / analogs & derivatives*
  • Adenosine / pharmacology
  • Animals
  • Antifungal Agents / pharmacology*
  • Avian Sarcoma Viruses*
  • Cell Line
  • Cell Transformation, Viral / drug effects*
  • Chick Embryo
  • Fibroblasts / metabolism
  • Kinetics
  • Methyltransferases / antagonists & inhibitors*
  • S-Adenosylhomocysteine / pharmacology
  • S-Adenosylmethionine / pharmacology
  • Structure-Activity Relationship

Substances

  • Antifungal Agents
  • S-Adenosylmethionine
  • S-Adenosylhomocysteine
  • Methyltransferases
  • Adenosine