Endovascular treatment of symptomatic radiation-induced basilar artery stenosis 25 years after medulloblastoma

Neuropediatrics. 2011 Jun;42(3):87-9. doi: 10.1055/s-0031-1283110. Epub 2011 Jul 7.

Abstract

Intracranial stenosis as late sequela after cerebral radiation therapy for medulloblastoma is an exceptionally rare finding. We report for the first time a case of 31-year-old patient with a history of medulloblastoma 25 years ago and now presenting with radiation-induced high-grade basilar stenosis and recurrent ischemic symptoms despite best medical therapy. The stenosis was treated successfully with angioplasty followed by stenting using a self-expandable microstent. Additionally, MRI revealed multiple cavernomas, illustrating that radiation-induced microbleeds may occur.

MeSH terms

  • Adult
  • Angioplasty, Balloon*
  • Humans
  • Male
  • Medulloblastoma / radiotherapy*
  • Radiotherapy / adverse effects*
  • Stents
  • Treatment Outcome
  • Vertebrobasilar Insufficiency / etiology
  • Vertebrobasilar Insufficiency / surgery*