Uterine carcinosarcoma

Curr Opin Oncol. 2011 Sep;23(5):531-6. doi: 10.1097/CCO.0b013e328349a45b.


Purpose of review: To summarize the clinical characteristics, epidemiology, and treatment of uterine carcinosarcoma.

Recent findings: Recent studies have suggested that uterine carcinosarcomas are aggressive neoplasms that carry a poor prognosis even when diagnosed at an early stage. Treatment is typically surgical. The ideal adjuvant treatment remains unknown. A number of recent studies have examined the influence of radiation, chemotherapy, and combinations of chemotherapy and radiation for uterine carcinosarcoma.

Summary: Carcinosarcoma is an aggressive neoplasm. A number of studies are underway to determine the optimal adjuvant therapy for these tumors.

Publication types

  • Review

MeSH terms

  • Carcinosarcoma / epidemiology*
  • Carcinosarcoma / pathology
  • Carcinosarcoma / therapy
  • Chemotherapy, Adjuvant
  • Clinical Trials as Topic
  • Combined Modality Therapy
  • Female
  • Humans
  • Neoplasm Recurrence, Local / therapy
  • Uterine Neoplasms / epidemiology*
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / therapy