The axon's balancing act: cis- and trans-interactions between Ephs and ephrins

Neuron. 2011 Jul 14;71(1):1-3. doi: 10.1016/j.neuron.2011.06.030.

Abstract

Ephrin ligands are known to be coexpressed with Eph receptors in certain populations of axons. In this issue of Neuron, Kao and Kania demonstrate the importance of ephrin/Eph cis-interaction for correct pathway selection by spinal motor axons in vivo.

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