Increasing ceftriaxone resistance in Salmonellae, Taiwan

Emerg Infect Dis. 2011 Jun;17(6):1086-90. doi: 10.3201/eid/1706.101949.

Abstract

In Taiwan, despite a substantial decline of Salmonella enterica serotype Choleraesuis infections, strains resistant to ciprofloxacin and ceftriaxone persist. A self-transferable bla(CMY-2)-harboring IncI1 plasmid was identified in S. enterica serotypes Choleraesuis, Typhimurium, Agona, and Enteritidis and contributed to the overall increase of ceftriaxone resistance in salmonellae.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use
  • Ceftriaxone / pharmacology*
  • Ceftriaxone / therapeutic use
  • Child, Preschool
  • DNA Gyrase / genetics
  • Drug Resistance, Bacterial / genetics
  • Gene Expression Regulation, Bacterial / drug effects
  • Humans
  • Infant
  • Microbial Sensitivity Tests
  • Mutation / genetics
  • Prevalence
  • Salmonella Infections / drug therapy
  • Salmonella Infections / epidemiology
  • Salmonella Infections / microbiology*
  • Salmonella Infections / mortality
  • Salmonella enterica / drug effects*
  • Salmonella enterica / genetics
  • Taiwan / epidemiology
  • beta-Lactamases / genetics

Substances

  • Anti-Bacterial Agents
  • Ceftriaxone
  • beta-lactamase CMY-2
  • beta-Lactamases
  • DNA Gyrase