Efficacy of antimicrobial triclosan-coated polyglactin 910 (Vicryl* Plus) suture for closure of the abdominal wall after colorectal surgery

Coll Antropol. 2011 Jun;35(2):439-43.

Abstract

This study compared Triclosan coated polyglactin 910 (Vicryl* Plus) with polyglactin 910 (Vicryl*) on abdominal wall healing in colorectal surgery patients. 184 patients with colorectal cancer were included in the study. In 91, the abdominal wall was closed with the Vicryl* Plus, and in 93 patients with Vicryl*. Demographic characteristics, biochemical inflammatory parameters, wound appearance, length of hospital stay, postoperative wound complications and post-incisional hernia were recorded. In the Vicryl* Plus group there was a shorter hospital stay (13.2 +/- 1.3 days; 21.4 +/- 2.8 respectively). In the Vicryl* Plus group inflammatory parameters decreased to normal within the first week whereas in the Vicryl* group remained increased. In the Vicryl* Plus group four patients had a wound discharge, seven had inflammatory reactions to the skin sutures. One dehiscence was noticed. In the Vicryl* group 12 patients had an SSI, 14 patients had inflammatory reactions to the skin sutures and 7 patients had a wound dehiscence. Closure of the abdominal wall using Vicryl* Plus decreases postoperative wound complications, length of hospital stay and is associated with a more rapid return of inflammatory markers to normal.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Abdominal Wall / surgery
  • Abdominal Wound Closure Techniques / instrumentation*
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Infective Agents, Local*
  • Colorectal Neoplasms / surgery*
  • Drug Delivery Systems / instrumentation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Polyglactin 910*
  • Surgical Wound Infection / prevention & control
  • Sutures*
  • Triclosan*

Substances

  • Anti-Infective Agents, Local
  • Polyglactin 910
  • Triclosan