Beyond stereospecificity: liquids and mesoscale organization of cytoplasm

Dev Cell. 2011 Jul 19;21(1):14-6. doi: 10.1016/j.devcel.2011.06.013.


The cytoplasm is not a homogenous solution but instead consists of large dynamic assemblies that arise from transient molecular interactions. Some of these structures have been shown to represent liquid droplets of concentrated protein and RNA. Liquid phase separation of cytoplasm may be a fundamental principle of cytoplasmic organization.

MeSH terms

  • Animals
  • Cell Compartmentation*
  • Cytoplasm / chemistry*
  • Cytoplasm / metabolism
  • Stereoisomerism