Self-organization of animal tissues: cadherin-mediated processes

Dev Cell. 2011 Jul 19;21(1):24-6. doi: 10.1016/j.devcel.2011.06.002.


Animal cells are capable of self-organizing into multicellular tissues, and important players in this process are cadherin receptors. Through the homophilic interactions of cadherins, cells adhere to one another. Cells can also dynamically change shapes or positions within tissue layers via cadherin-cytoskeleton interactions and become arranged into various architectures.

MeSH terms

  • Animals
  • Cadherins / metabolism*
  • Cell Adhesion
  • Developmental Biology
  • Organogenesis*


  • Cadherins