Evaluation and management of BK virus-associated nephropathy following allogeneic hematopoietic cell transplantation

Biol Blood Marrow Transplant. 2011 Nov;17(11):1589-93. doi: 10.1016/j.bbmt.2011.07.010. Epub 2011 Jul 20.


BK virus nephropathy is a common cause of graft loss in kidney transplant recipients. Cases of BK nephropathy following allogeneic hematopoietic cell transplantation (HCT) are underreported. An increased incidence of BK virus-associated nephropathy is being seen in the setting of more profound and prolonged immunosuppression following solid organ transplantation and HCT. We will review diagnostic and treatment modalities for BK-associated nephropathy following allogeneic HCT.

MeSH terms

  • Antiviral Agents / therapeutic use
  • BK Virus / isolation & purification*
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Immunohistochemistry
  • Nephritis, Interstitial / drug therapy
  • Nephritis, Interstitial / etiology*
  • Nephritis, Interstitial / pathology
  • Nephritis, Interstitial / virology
  • Transplantation, Homologous


  • Antiviral Agents