Clopidogrel use throughout pregnancy in a patient with a drug-eluting coronary stent

Obstet Gynecol. 2011 Aug;118(2 Pt 2):432-433. doi: 10.1097/AOG.0b013e318213d024.


Background: Little information regarding the potential implications of drug-eluting stents and clopidogrel on pregnancy exists.

Case: We report a case of a 27-year-old woman who received a drug-eluting coronary stent for an acute myocardial infarction and was started on clopidogrel as treatment. She was on clopidogrel when she conceived and delivered a child by cesarean. Her postpartum course was complicated by postoperative bleeding requiring transfusion.

Conclusion: This case highlights the perinatal and peripartum concerns of these interventions in women of childbearing age. It suggests that cesarean delivery is associated with an elevated risk of perioperative bleeding and may best be approached like other surgical procedures, with the optimal timing of surgery, when feasible, being 5 or more days after the discontinuation of clopidogrel.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cesarean Section
  • Clopidogrel
  • Cocaine / administration & dosage
  • Drug-Eluting Stents*
  • Female
  • Humans
  • Infant, Newborn
  • Myocardial Infarction / drug therapy
  • Platelet Aggregation Inhibitors / adverse effects
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Pregnancy
  • Pregnancy Complications, Hematologic / chemically induced
  • Ticlopidine / adverse effects
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / therapeutic use
  • Treatment Outcome


  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Cocaine
  • Ticlopidine