Excess electron localization in solvated DNA bases

Phys Rev Lett. 2011 Jun 10;106(23):238108. doi: 10.1103/PhysRevLett.106.238108. Epub 2011 Jun 10.

Abstract

We present a first-principles molecular dynamics study of an excess electron in condensed phase models of solvated DNA bases. Calculations on increasingly large microsolvated clusters taken from liquid phase simulations show that adiabatic electron affinities increase systematically upon solvation, as for optimized gas-phase geometries. Dynamical simulations after vertical attachment indicate that the excess electron, which is initially found delocalized, localizes around the nucleobases within a 15 fs time scale. This transition requires small rearrangements in the geometry of the bases.

MeSH terms

  • DNA / chemistry*
  • Electrons*
  • Gases
  • Hydrogen Bonding
  • Molecular Dynamics Simulation
  • Quantum Theory
  • Solvents / chemistry*
  • Thymine / chemistry
  • Time Factors
  • Water / chemistry*

Substances

  • Gases
  • Solvents
  • Water
  • DNA
  • Thymine