Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate

Int J Toxicol. 2011 May;30(3 Suppl):40S-53S. doi: 10.1177/1091581811406987.


Sesamum indicum (sesame) seed oil and related cosmetic ingredients are derived from Sesamum indicum. Sesamum indicum (sesame) seed oil, sesamum indicum (sesame) oil unsaponifiables, and hydrogenated sesame seed oil function as conditioning agents. Sodium sesameseedate functions as a cleansing agent, emulsifying agent, and a nonaqueous viscosity increasing agent. These ingredients are neither skin irritants, sensitizers, teratogens, nor carcinogens at exposures that would result from cosmetic use. Both animal and human data relevant to the cosmetic use of these ingredients were reviewed. The CIR Expert Panel concluded that these ingredients are safe in the present practices of use and concentration as described in this safety assessment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Consumer Product Safety
  • Cosmetics / adverse effects*
  • Cosmetics / chemistry*
  • Food Additives / adverse effects
  • Food Additives / chemistry
  • Humans
  • Hydrogenation
  • Molecular Structure
  • Sesame Oil / adverse effects*
  • Sesame Oil / chemistry*
  • Sesamum / chemistry*
  • Soaps / chemistry*
  • Toxicity Tests


  • Cosmetics
  • Food Additives
  • Soaps
  • Sesame Oil