Effects of common dental materials used in preventive or operative dentistry on dentin permeability and remineralization

Oper Dent. 2011 Mar-Apr;36(2):222-30. doi: 10.2341/10-225-L.


The aim of this study was to evaluate the dentin remineralization induced by bioactive substances contained in common dental materials used in preventive and operative dentistry. Several materials were applied on human dentin segments. Dentin permeability was quantified using a fluid filtration system working at 20 cm H(2)O. Micro-Raman, SEM-EDX, and microhardness calculation were used to evaluate changes in the mineralization of dentin. Dentin treated with the prophylactic materials showed different dentin permeability values, in particular subsequent to immersion in remineralizing solutions (RSS). The bioactive glass (Sylc) was the only substance able to reduce dentin permeability after immersion in remineralizing solution and to show hydroxyapatite precipitation as a sign of dentin remineralization. The reduction in dentin permeability obtained after the application of the other prophylactic materials used in this study was due to the presence of the remnant material in the dentinal tubules, with no remineralization effect after storage in remineralizing solution. In conclusion, the results indicated that bioactive glass prophy powder may induce immediate remineralization of dentin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acid Etching, Dental
  • Arginine / pharmacology
  • Biocompatible Materials / pharmacology*
  • Calcium Carbonate / pharmacology
  • Caseins / pharmacology
  • Ceramics
  • Dental Materials / pharmacology*
  • Dental Prophylaxis*
  • Dentin / drug effects*
  • Dentin Desensitizing Agents / pharmacology
  • Dentin Permeability / drug effects*
  • Durapatite / analysis
  • Electron Probe Microanalysis
  • Filtration / methods
  • Glass
  • Glycine / pharmacology
  • Hardness
  • Humans
  • Microscopy, Confocal
  • Microscopy, Electron, Scanning
  • Oxalates / pharmacology
  • Smear Layer
  • Sodium Bicarbonate / pharmacology
  • Spectrum Analysis, Raman
  • Tooth Remineralization*


  • Biocompatible Materials
  • Caseins
  • Dental Materials
  • Dentin Desensitizing Agents
  • NovaMin
  • Oxalates
  • bioactive glass 45S5
  • casein phosphopeptide-amorphous calcium phosphate nanocomplex
  • Sodium Bicarbonate
  • Durapatite
  • Arginine
  • Calcium Carbonate
  • Glycine