PET imaging of CXCR4 receptors in cancer by a new optimized ligand

ChemMedChem. 2011 Oct 4;6(10):1789-91. doi: 10.1002/cmdc.201100320. Epub 2011 Jul 20.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Contrast Media / chemistry*
  • Contrast Media / pharmacokinetics
  • Coordination Complexes / chemistry
  • Coordination Complexes / pharmacokinetics
  • Gallium Radioisotopes / chemistry
  • Heterocyclic Compounds, 1-Ring / chemistry
  • Humans
  • Ligands*
  • Mice
  • Mice, Nude
  • Neoplasms / diagnostic imaging
  • Positron-Emission Tomography*
  • Receptors, CXCR4 / antagonists & inhibitors*
  • Receptors, CXCR4 / metabolism
  • Structure-Activity Relationship
  • Tissue Distribution
  • Transplantation, Heterologous

Substances

  • Contrast Media
  • Coordination Complexes
  • Gallium Radioisotopes
  • Heterocyclic Compounds, 1-Ring
  • Ligands
  • Receptors, CXCR4
  • 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid