Lectins but not antifungal proteins exhibit anti-nematode activity

S Zhao; Y X Guo; Q H Liu; H X Wang; T B Ng

doi:10.1016/j.etap.2009.05.003

Lectins but not antifungal proteins exhibit anti-nematode activity

Environ Toxicol Pharmacol. 2009 Sep;28(2):265-8. doi: 10.1016/j.etap.2009.05.003. Epub 2009 May 14.

Authors

S Zhao¹, Y X Guo, Q H Liu, H X Wang, T B Ng

Affiliation

¹ State Key Laboratory for Agrobiotechnology and Department of Microbiology, China Agricultural University, Beijing, China.

PMID: 21784014
DOI: 10.1016/j.etap.2009.05.003

Abstract

A variety of lectins and antifungal proteins were tested for toxicity against the plant parasitic nematodes Ditylenchus dipsaci and Heterodera glycines. It was found that lectins from the mushrooms Xylaria hypoxylon, Agrocybe cylindracea and Tricholoma mongolicum (TML-1) were the most potent against D. dipsaci, with EC(50) being 4.7, 9, and 20mg/ml, respectively. Lectins from Pseudostellaria heterophylla, samta tomato, and the mushrooms T. mongolicum (TML-2), Ganoderma lucidum, and Boletus edulis, and antifungal proteins from Ginkgo biloba toward D. dipsaci and pumpkin Cucurbita moschata had much lower anti-nematode potencies and could be considered as inactive for practical purposes. All lectins except that from P.heterophylle were potent against H.glycines.