A near-infrared reversible fluorescent probe for peroxynitrite and imaging of redox cycles in living cells

Kehua Xu; Huachao Chen; Jiangwei Tian; Baiyu Ding; Yanxia Xie; Mingming Qiang; Bo Tang

doi:10.1039/c1cc12994e

A near-infrared reversible fluorescent probe for peroxynitrite and imaging of redox cycles in living cells

Chem Commun (Camb). 2011 Sep 7;47(33):9468-70. doi: 10.1039/c1cc12994e. Epub 2011 Jul 22.

Authors

Kehua Xu¹, Huachao Chen, Jiangwei Tian, Baiyu Ding, Yanxia Xie, Mingming Qiang, Bo Tang

Affiliation

¹ Key Laboratory of Molecular and Nano Probes, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, College of Chemical Engineering and Materials Science, Shandong Normal University, Jinan, 250014, China.

PMID: 21785760
DOI: 10.1039/c1cc12994e

Abstract

BzSe-Cy is a small-molecule fluorescent probe containing Se, which can respond reversibly to changes in ONOO(-) or reduced ascorbate and exhibit high sensitivity and selectivity for ONOO(-).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Carbocyanines / chemistry*
Cell Line, Tumor
Fluorescent Dyes / chemistry*
Hydrogen-Ion Concentration
Infrared Rays
Mice
Microscopy, Confocal
Organoselenium Compounds / chemistry*
Oxidation-Reduction
Peroxynitrous Acid / chemistry*
Peroxynitrous Acid / metabolism

Substances

Carbocyanines
Fluorescent Dyes
Organoselenium Compounds
Peroxynitrous Acid