Current concepts and management of glioblastoma

Ann Neurol. 2011 Jul;70(1):9-21. doi: 10.1002/ana.22425.


Glioblastoma is the most common malignant primary brain tumor in adults. Its often rapid clinical course, with many medical and psychosocial challenges, requires a multidisciplinary management. Modern multimodality treatment and care improve patients' life expectancy and quality of life. This review covers major aspects of care of glioblastoma patients with a focus on the management of common symptoms and complications. We aim to provide a guide for clinicians confronted with glioblastoma patients in their everyday practice.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain Edema / etiology
  • Brain Edema / psychology
  • Brain Edema / therapy
  • Brain Neoplasms / complications
  • Brain Neoplasms / psychology
  • Brain Neoplasms / therapy*
  • Clinical Trials as Topic / methods
  • Disease Management
  • Glioblastoma / complications
  • Glioblastoma / psychology
  • Glioblastoma / therapy*
  • Humans
  • Quality of Life / psychology
  • Risk Factors
  • Seizures / etiology
  • Seizures / psychology
  • Seizures / therapy