Who has advanced heart failure?: definition and epidemiology

Congest Heart Fail. Jul-Aug 2011;17(4):160-8. doi: 10.1111/j.1751-7133.2011.00246.x. Epub 2011 Jul 21.


Summarizing current guidelines and advanced heart failure (AHF) clinical trials/registries, this review focuses on the current definition of AHF and emphasizes the secular trends in this definition over the last two decades. Further, clinical, imaging, hemodynamic, functional capacity and biomarker parameters that may aid clinicians to better recognize patients with AHF are reviewed. Finally, we review the limited data concerning the epidemiology of AHF which to date has been poorly characterized.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Cardiac Resynchronization Therapy
  • Disease Progression
  • Echocardiography, Doppler
  • Heart Failure / diagnosis*
  • Heart Failure / epidemiology*
  • Heart Failure / physiopathology
  • Heart Failure / therapy
  • Heart-Assist Devices
  • Hemodynamics
  • Hospitalization / statistics & numerical data
  • Humans
  • Prevalence
  • Prognosis
  • Ventricular Dysfunction / epidemiology